Duopil 1/500 Tablet PR

Category: Anti-diabetic combination drug
Composition: Glimepiride (1mg) + Metformin (500mg)

Uses

• Treatment of Type 2 Diabetes Mellitus in adults by controlling blood sugar levels.

Key Benefits

• Dual Action:

  • Glimepiride stimulates insulin release from the pancreas.

  • Metformin reduces liver glucose production and improves insulin sensitivity.

• Lowers risk of diabetes complications (kidney damage, nerve problems, etc.).

Dosage & Administration

• Take once daily with food to avoid stomach upset.

• Do not stop abruptly without consulting your doctor.

• Missed Dose: Take ASAP, but skip if close to the next dose.

Side Effects

• Common: Hypoglycemia (sweating, dizziness, headache), nausea, diarrhea, stomach pain.

• Others: Weight gain, taste changes, upper respiratory infections.

Safety Warnings

• Avoid Alcohol: Increases hypoglycemia risk and lactic acidosis (with metformin).

• Contraindications:

  • Type 1 diabetes, diabetic ketoacidosis.

  • Severe kidney/liver disease.

• Special Precautions:

  • Pregnancy/Breastfeeding: Unsafe; consult doctor.

  • Kidney/Liver Impairment: Dose adjustment needed; avoid in severe cases.

  • Driving: Caution if hypoglycemia symptoms occur.

Lifestyle Tips

• Combine with healthy diet, exercise, and weight management.

• Monitor blood sugar regularly.

• Carry fast-acting glucose (juice, candy) to manage hypoglycemia.

Why Prescribed?

• Effective for long-term blood sugar control when monotherapy fails.

Note: Individual response may vary. Always follow your doctor’s advice.