Overview
Nulong-Trio Tablet is a triple-combination antihypertensive medication used to treat high blood pressure (hypertension) when single-drug therapy is ineffective. It helps lower blood pressure, reducing the risk of heart attack, stroke, and kidney damage.
Key Components & Mechanism of Action
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Olmesartan Medoxomil (ARB) – Blocks angiotensin receptors, relaxing blood vessels.
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Cilnidipine (CCB) – Inhibits calcium entry, dilating blood vessels.
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Chlorthalidone (Diuretic) – Removes excess water/salt, reducing blood volume.
Dosage & Administration
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Take with food to improve absorption.
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Swallow whole (do not chew/crush).
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Avoid taking near bedtime (due to increased urination).
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Regular use is essential—even if asymptomatic.
Benefits
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Effective BP control by targeting multiple pathways.
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Reduces long-term risks (stroke, heart attack, kidney disease).
Common Side Effects
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Ankle swelling, dizziness, headache, fatigue
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Palpitations, sleepiness, upset stomach
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Increased uric acid, glucose intolerance
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Taste changes, dry mouth, electrolyte imbalance
Precautions & Warnings
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Avoid alcohol (increases drowsiness/dizziness).
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Unsafe in pregnancy (risk to fetus).
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Caution in breastfeeding (may pass into milk).
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Do not drive if drowsy or dizzy.
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Monitor kidney/liver function, electrolytes, and blood sugar.
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Severe kidney/liver disease: Use with caution or avoid.
Missed Dose
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Take as soon as remembered, but skip if close to the next dose. Do not double dose.
Conclusion
Nulong-Trio is a potent antihypertensive for resistant cases but requires strict adherence and monitoring due to possible side effects and interactions. Always follow your doctor’s advice and report any persistent adverse effect
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