Product Description

Rifakem-400 Tablet, manufactured by Alkem Pharma, contains Rifampicin 400mg, a powerful antibiotic used primarily in the treatment of tuberculosis (pulmonary and extrapulmonary) and other susceptible bacterial infections.

Rifakem-400 is typically prescribed as part of a combination therapy along with other antitubercular drugs such as Isoniazid, Pyrazinamide, and Ethambutol. This ensures effective eradication of TB bacteria while preventing drug resistance. It helps reduce symptoms like fever, cough, night sweats, and fatigue while promoting recovery.

Uses

• Treatment of tuberculosis (TB)

• Part of combination therapy for multidrug-resistant TB

• Management of other bacterial infections

• Helps prevent spread of TB

• Reduces symptoms like fever, cough, and fatigue

Key Benefits

• Highly effective antitubercular antibiotic

• Prevents bacterial growth and infection spread

• Supports combination therapy for drug-resistant TB

• Helps improve patient recovery and treatment outcomes

• Reduces TB-related symptoms and complications

How to Use

• Take the tablet as prescribed by your doctor, usually once daily.

• Swallow whole with water, preferably on an empty stomach for better absorption.

• Complete the full prescribed course to avoid relapse and drug resistance.

How It Works

• Rifampicin (400mg): Blocks bacterial RNA synthesis, preventing bacteria from multiplying and helping the body eliminate the infection effectively.

Side Effects

• Orange-red discoloration of urine, sweat, and tears (normal effect)

• Nausea, vomiting, or diarrhea

• Liver enzyme elevation (requires monitoring)

• Rare: allergic reactions, jaundice, or severe liver injury

Precautions & Warnings

• Monitor liver function during prolonged therapy.

• Inform your doctor about allergies or liver/kidney problems.

• Avoid alcohol while on this medicine.

• Pregnant or breastfeeding women should use only under medical supervision.

• Always complete the full treatment course to prevent drug resistance.

Storage Instructions

• Store in a cool, dry place below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.

FAQs

What is Rifakem-400 Tablet used for?

It is used to treat tuberculosis (TB) and other bacterial infections as part of combination therapy.

Can Rifakem-400 be taken alone for TB?

No, TB treatment usually requires combination therapy to prevent resistance.

Why does urine turn orange while taking Rifakem?

This is a normal, harmless effect of Rifampicin.

Is liver monitoring necessary?

Yes, liver function tests are recommended during prolonged therapy to avoid liver damage.

Can I stop taking Rifakem-400 once I feel better?

No, completing the full prescribed course is essential to prevent relapse and drug resistance.