Key Highlights

• Class: Tricyclic antidepressant (TCA)

• Uses:

  • Depression, anxiety, migraine prevention

  • Neuropathic pain, insomnia, bed-wetting, OCD

• Dosage:

  • Taken at bedtime (causes drowsiness).

  • Start with a low dose, gradually increased under medical supervision.

  • Do not stop abruptly (risk of withdrawal symptoms).

Side Effects

• Common: Dry mouth, drowsiness, dizziness, constipation, weight gain, blurred vision.

• Serious (Rare): Irregular heartbeat, seizures, mood changes (aggression/confusion), severe hypotension.

Safety Advice

• Alcohol: Avoid (increases sedation risk).

• Driving: Unsafe (impairs alertness).

• Pregnancy/Breastfeeding: Consult doctor (potential risks to baby).

• Kidney/Liver: Use with caution (dose adjustment may be needed; avoid in severe liver disease).

How It Works

• Blocks reuptake of serotonin & noradrenaline (improves mood).

• Reduces pain signals in nerves (for neuropathic pain/migraine).

If You Miss a Dose

• Take ASAP, but skip if close to the next dose. Never double dose.

Note: Always follow your doctor’s instructions. Report any persistent or severe side effects.