Tryptomer G 100 mg/10 mg Tablet is a combination medication containing Gabapentin (100 mg) and Amitriptyline (10 mg), primarily used to treat neuropathic pain (nerve pain caused by conditions like diabetes, shingles, or spinal cord injury).
Key Features:
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Mechanism of Action:
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Gabapentin (an alpha-2-delta ligand) reduces nerve pain by modulating calcium channels.
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Amitriptyline (a tricyclic antidepressant) increases serotonin and noradrenaline levels, blocking pain signals in the brain.
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Dosage & Administration:
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Take once daily at bedtime (or as prescribed) with or without food.
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Swallow whole; do not crush or chew.
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Do not stop suddenly—taper under medical supervision to avoid withdrawal effects.
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Benefits:
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Relieves chronic nerve pain, improves mood, sleep, and quality of life.
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May take a few weeks to show full effects; continue as prescribed.
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Common Side Effects:
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Constipation, dry mouth, dizziness, drowsiness, weight gain, blurred vision, difficulty urinating.
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Avoid alcohol, driving, or operating machinery until effects are known.
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Precautions & Warnings:
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Avoid alcohol (increases dizziness/sedation).
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Not safe in pregnancy/breastfeeding (consult doctor).
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Use cautiously in liver disease (avoid in severe cases).
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Kidney patients may require dose adjustments.
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Do not take with antacids (reduces absorption).
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Missed Dose?
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Take as soon as remembered, but skip if close to next dose. Do not double dose.
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Storage:
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Keep at room temperature, away from moisture and light.
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Conclusion:
Tryptomer G is effective for neuropathic pain but requires careful use due to side effects like drowsiness and weight gain. Always follow your doctor’s instructions and report any unusual symptoms.
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