Tryptomer G 100 mg/10 mg Tablet is a combination medication containing Gabapentin (100 mg) and Amitriptyline (10 mg), primarily used to treat neuropathic pain (nerve pain caused by conditions like diabetes, shingles, or spinal cord injury).

Key Features:

• Mechanism of Action:

  • Gabapentin (an alpha-2-delta ligand) reduces nerve pain by modulating calcium channels.

  • Amitriptyline (a tricyclic antidepressant) increases serotonin and noradrenaline levels, blocking pain signals in the brain.

• Dosage & Administration:

  • Take once daily at bedtime (or as prescribed) with or without food.

  • Swallow whole; do not crush or chew.

  • Do not stop suddenly—taper under medical supervision to avoid withdrawal effects.

• Benefits:

  • Relieves chronic nerve pain, improves mood, sleep, and quality of life.

  • May take a few weeks to show full effects; continue as prescribed.

• Common Side Effects:

  • Constipation, dry mouth, dizziness, drowsiness, weight gain, blurred vision, difficulty urinating.

  • Avoid alcohol, driving, or operating machinery until effects are known.

• Precautions & Warnings:

  • Avoid alcohol (increases dizziness/sedation).

  • Not safe in pregnancy/breastfeeding (consult doctor).

  • Use cautiously in liver disease (avoid in severe cases).

  • Kidney patients may require dose adjustments.

  • Do not take with antacids (reduces absorption).

• Missed Dose?

  • Take as soon as remembered, but skip if close to next dose. Do not double dose.

• Storage:

  • Keep at room temperature, away from moisture and light.

Conclusion:

Tryptomer G is effective for neuropathic pain but requires careful use due to side effects like drowsiness and weight gain. Always follow your doctor’s instructions and report any unusual symptoms.