Duopil-HS 2/850 Tablet PR

Category: Anti-diabetic combination drug
Composition: Glimepiride (2mg) + Metformin (850mg)
Used for: Type 2 Diabetes Mellitus in adults

Key Benefits:

• Controls blood sugar by increasing insulin production (Glimepiride) and reducing liver glucose output (Metformin).

• Lowers risk of diabetes complications (kidney damage, nerve problems, etc.).

Dosage & Administration:

• Take once daily with food to avoid stomach upset.

• Do not stop without consulting your doctor.

• Missed dose: Take ASAP; skip if close to next dose.

Common Side Effects:

• Hypoglycemia (sweating, dizziness, headache – treat with sugary food/juice).

• Nausea, diarrhea, stomach pain, weight gain.

Serious Warnings:

• Avoid alcohol (increases hypoglycemia risk).

• Contraindicated in:

  • Type 1 diabetes or diabetic ketoacidosis.

  • Severe kidney/liver disease.

  • Pregnancy/breastfeeding (unsafe).

• Use cautiously in heart, kidney, or liver disease.

Lifestyle Tips:

• Combine with diet, exercise, and weight management.

• Monitor blood sugar regularly.

Mechanism of Action:

• Glimepiride: Stimulates pancreas to release insulin.

• Metformin: Reduces liver glucose production + improves insulin sensitivity.

Note: Regular blood tests (kidney/liver function) may be required.