Description
Product Description
Duopil HS 1/850 Tablet is designed for people with type 2 diabetes whose blood sugar is not controlled by lifestyle changes alone. It contains a combination of glimepiride, which helps the pancreas release more insulin, and sustained-release metformin, which reduces the liver’s glucose production and improves the body’s response to insulin. The sustained-release form of metformin ensures a steady drug release, reducing side effects and improving tolerability.
Uses
Management of type 2 diabetes mellitus
Helps maintain blood glucose levels when diet and exercise are not enough
Key Benefits
Dual mechanism: increases insulin and decreases sugar production
Long-acting control with SR metformin
Helps control both fasting and post-meal blood sugar
May reduce risk of long-term diabetes complications
How to Use
Take once daily, or as prescribed by your doctor
Swallow the tablet whole with water
Best taken with food to reduce gastrointestinal side effects
Do not chew, break, or crush the tablet
How It Works
Glimepiride: Stimulates the pancreas to release more insulin, reducing blood sugar
Metformin SR: Reduces glucose production in the liver and improves insulin sensitivity
The SR form allows gradual absorption, maintaining stable blood levels and reducing stomach discomfort
Side Effects
Hypoglycemia (low blood sugar) — signs: sweating, dizziness, shaking
Nausea, diarrhea, stomach pain
Headache
Weight gain
Gastrointestinal discomfort
Precautions & Warnings
Avoid skipping meals — risk of low blood sugar
Monitor blood sugar regularly
Avoid excessive alcohol — increases risk of hypoglycemia
Not to be used in type 1 diabetes or diabetic ketoacidosis
Use with caution in kidney or liver problems
Inform your doctor if you are pregnant or breastfeeding
Do not stop the medicine suddenly — follow your doctor’s tapering plan
Storage Instructions
Store in a cool, dry place
Keep away from direct sunlight
Keep the medicine out of reach of children
FAQs
What is Duopil HS 1/850 Tablet?
It’s a medicine for type 2 diabetes that combines two drugs for better blood sugar control.
When should I take it?
Once a day, usually with food to avoid stomach discomfort.
What if I skip a dose?
If it’s almost time for your next dose, skip the missed one — do not double up.
Can it cause low blood sugar?
Yes, because of glimepiride. Signs include sweating, shaking, dizziness; always keep a fast-acting sugar source ready.
Can I drink alcohol while on this medicine?
It’s not recommended, as alcohol can worsen the risk of low blood sugar.







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