Description
Product Description
4-Sachet Plus from Meneesh Pharmaceuticals is an advanced anti-tubercular formulation designed to improve treatment compliance in patients with tuberculosis. It comes in a single-dose sachet form, containing a precise combination of four first-line anti-TB drugs (Rifampicin, Isoniazid, Ethambutol, and Pyrazinamide) along with Pyridoxine (Vitamin B6) to reduce the risk of drug-induced neuropathy. The sachet is granulated using NODS (New Oral Drug System) technology, making it easier to swallow and ensuring uniform drug absorption. With its convenient once-daily sachet format and orange flavour, 4-Sachet Plus improves patient adherence and enhances therapeutic outcomes.
Uses
- Treatment of pulmonary and extrapulmonary tuberculosis
- Effective in both new and continuation phases of TB treatment (as prescribed)
- Helps reduce pill burden and simplifies anti-TB therapy
Key Benefits
- Convenient Sachet Form – One sachet covers the full daily dose of multiple TB drugs
- Improves Compliance – Reduces pill load, making it easier for patients to complete treatment
- Balanced Combination – Contains all four essential anti-TB drugs in WHO-recommended proportions
- Enhanced Absorption – NODS granular technology ensures better bioavailability
- Added Vitamin B6 – Prevents peripheral neuropathy caused by Isoniazid
How to Use
- Take one sachet daily or as directed by your doctor.
- Mix the sachet contents with water or juice and consume immediately.
- Follow the full treatment course without skipping doses to avoid drug resistance.
How It Works
4-Sachet Plus combines four first-line anti-tubercular drugs:
- Rifampicin: Kills TB bacteria by inhibiting RNA synthesis.
- Isoniazid: Stops bacterial cell wall formation.
- Ethambutol: Prevents bacterial growth by inhibiting cell wall enzymes.
- Pyrazinamide: Works inside cells to kill dormant TB bacteria.
- Pyridoxine (Vitamin B6): Protects against nerve damage associated with Isoniazid.
Together, they provide a powerful and complete therapy against tuberculosis.
Side Effects
- Nausea, vomiting, or stomach upset
- Mild skin rash or itching
- Loss of appetite
- Fatigue
- Rare: liver issues, peripheral neuropathy, or vision disturbances
(Consult your doctor if any side effects persist or worsen.)
Precautions & Warnings
- Not recommended for patients with severe liver or kidney disease unless prescribed.
- Avoid alcohol during treatment.
- Pregnant and breastfeeding women should take only under medical advice.
- Regular liver function tests may be advised during treatment.
- Do not stop the treatment early to avoid drug resistance.
Storage Instructions
- Store in a cool, dry place below 25°C.
- Keep away from direct sunlight and moisture.
- Keep out of reach of children.
FAQs
What is 4-Sachet Plus used for?
It is used for the treatment of tuberculosis by providing a complete fixed-dose combination of four anti-TB drugs in one sachet.
Can I take 4-Sachet Plus without water?
No, always mix the sachet contents in water or juice and consume immediately for best results.
Does 4-Sachet Plus contain Vitamin B6?
Yes, it contains Pyridoxine (Vitamin B6) to prevent Isoniazid-induced neuropathy.
How long should I take 4-Sachet Plus?
The duration depends on your doctor’s prescription and the TB treatment phase (usually 6–9 months).
Can children use 4-Sachet Plus?
Use in children should be strictly under a pediatrician’s guidance.










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