Avil Injection

Description

Product Description

Avil Injection contains Pheniramine Maleate, a first-generation H1 antihistamine. The commonly available presentation is a 2 ml ampoule, with each ml containing 22.75 mg of Pheniramine Maleate.

It is used when rapid or medically supervised management of allergic symptoms is required. Pheniramine works by blocking the action of histamine, a chemical involved in many allergic reactions. Depending on the clinical situation, it may be used for conditions involving itching, hives, allergic skin reactions, certain drug-related allergic reactions and other histamine-mediated symptoms.

Because Avil can produce drowsiness and other effects on the central nervous system, the injection should be administered only by a qualified healthcare professional. The underlying cause and severity of the allergic reaction should always be assessed before treatment.

Uses

• Relief of symptoms associated with allergic reactions.
• Management of urticaria or hives.
• Relief of itching associated with selected allergic skin conditions.
• May be used for allergic reactions related to medicines or other triggers.
• May be prescribed for allergic conjunctivitis and certain respiratory allergy symptoms.
• May be used in selected cases of nausea, vomiting or vertigo associated with labyrinthine disorders when specifically prescribed.

Key Benefits

• Provides Pheniramine Maleate through an injectable route.
• Blocks histamine-mediated allergic symptoms.
• Can help reduce itching, wheals and other manifestations of allergic reactions.
• Suitable for supervised treatment when an injectable antihistamine is considered necessary.
• May be useful when oral antihistamine administration is not appropriate in the clinical situation.

How to Use

• Avil Injection must be administered by a doctor, nurse or other qualified healthcare professional.
• Use the injection exactly as prescribed by your doctor.
• The route of administration and amount depend on the patient’s condition and clinical requirements.
• Do not self-inject the medicine.
• Do not use an opened or partially used ampoule for a later dose.
• Tell the healthcare professional about all medicines and supplements you are taking before receiving the injection.
• Remain under observation when advised, particularly if the injection has been given for an acute allergic reaction.

How It Works

Pheniramine Maleate blocks H1 histamine receptors. Histamine contributes to symptoms such as itching, redness, swelling, runny nose and other features of an allergic response. By reducing histamine’s action at these receptors, Pheniramine helps lessen these symptoms. As a first-generation antihistamine, it can also enter the central nervous system, which explains why drowsiness and reduced alertness may occur after administration.

Side Effects

• Drowsiness or sleepiness.
• Dizziness.
• Dry mouth.
• Blurred vision.
• Headache.
• Nausea.
• Stomach discomfort.
• Constipation.
• Difficulty passing urine.
• Increased sensitivity to sunlight may occur in some people.
• Injection-site discomfort may occur.

Contact your doctor if any side effect is severe, persistent or concerning.

Precautions & Warnings

• Pheniramine can cause significant drowsiness and reduced alertness. Avoid driving, operating machinery or performing other hazardous activities after receiving the injection until you are fully alert.
• Alcohol and other medicines that cause sedation can increase drowsiness and impairment. Tell your doctor before using them together.
• Inform your doctor if you have glaucoma, particularly narrow-angle glaucoma, because antihistamines with anticholinergic effects may worsen the condition.
• Tell your doctor if you have difficulty passing urine, prostate enlargement or another urinary obstruction.
• Inform your doctor if you have asthma, chronic respiratory disease or other breathing problems.
• Tell your doctor about epilepsy, cardiovascular disease or other significant medical conditions before treatment.
• Pheniramine may cause anticholinergic effects such as dry mouth, blurred vision and reduced sweating. Take appropriate care in hot environments and report severe symptoms.
• Tell your doctor about all prescription medicines, over-the-counter products, sleeping medicines, sedatives and other antihistamines you use.
• Avoid taking other antihistamines at the same time unless specifically advised by a healthcare professional.
• Consult your doctor before using Avil during pregnancy or breastfeeding.
• Older adults may be more sensitive to drowsiness, dizziness and anticholinergic effects and may require closer monitoring.
• Avil Injection is intended for symptomatic relief and does not replace emergency management of severe anaphylaxis. Patients with a serious allergic reaction require appropriate emergency treatment and medical monitoring.
• Seek urgent medical attention for breathing difficulty, swelling of the throat or tongue, fainting, severe dizziness or rapidly worsening allergic symptoms.

Storage Instructions

• Store below 25°C unless the product label specifies otherwise.
• Keep the ampoule in its original packaging until use.
• Protect from excessive heat and direct sunlight.
• Do not freeze.
• Inspect the solution before administration and do not use it if it is discoloured or contains visible particles.
• Keep out of reach and sight of children.
• Do not use after the expiry date printed on the package.

FAQs

Q: What is Avil Injection used for?
A: Avil Injection is used under medical supervision for allergic conditions such as hives, itching and other histamine-related allergic symptoms.

Q: What does Avil Injection contain?
A: Avil Injection contains Pheniramine Maleate 22.75 mg/ml.

Q: Is Avil Injection a prescription medicine?
A: Yes. Avil Injection is a prescription injectable antihistamine and should be administered by a qualified healthcare professional.

Q: Can Avil Injection cause sleepiness?
A: Yes. Drowsiness and reduced alertness are common effects of Pheniramine. Avoid driving or operating machinery until the effect has completely worn off.

Q: Is Avil Injection used for severe allergic reactions?
A: It may be used as part of medical treatment for certain allergic reactions, but it does not replace emergency treatment required for anaphylaxis or severe airway or circulatory problems.

Q: Who manufactures Avil Injection?
A: Avil Injection is manufactured and marketed by Sanofi India Ltd. The commonly available presentation is a 2 ml ampoule.