Clavix-AS 75 Tablet

Description

Product Description

Clavix-AS 75 Tablet combines two antiplatelet medicines that reduce platelet activation through different pathways. Clopidogrel blocks the platelet P2Y12 ADP receptor, while Aspirin inhibits cyclooxygenase-1 and reduces thromboxane A2 formation. Their combined effect lowers the tendency of platelets to stick together and form clots within arteries.

This type of dual antiplatelet treatment is commonly used for a defined period in selected cardiovascular conditions, including certain acute coronary syndromes and after coronary interventions such as stent placement. The required duration depends on the patient’s diagnosis, bleeding risk and procedure history, so treatment should always follow the cardiologist’s instructions.

Clavix-AS is not intended for casual or preventive use without a clear medical indication. Because both ingredients affect blood clotting, regular treatment requires particular attention to bleeding symptoms and interactions with other medicines.

Uses

• Prevention of blood-clot-related cardiovascular events in selected patients with acute coronary syndrome.
• May be prescribed after certain coronary procedures, including placement of a coronary stent.
• May be used after certain heart attacks when dual antiplatelet therapy is indicated.
• Helps reduce platelet aggregation in patients for whom combined Aspirin and Clopidogrel treatment is appropriate.

Key Benefits

• Combines two antiplatelet agents with different mechanisms.
• Helps reduce platelet clumping and arterial clot formation.
• Provides both active ingredients in a single oral tablet.
• Can form part of a prescribed treatment plan following selected coronary events or interventions.
• May simplify treatment when both medicines are required together.

How to Use

• Take Clavix-AS 75 exactly as prescribed by your doctor.
• Swallow the tablet whole with water.
• It is generally taken with or after food when advised, which may help reduce stomach irritation.
• Take it consistently according to the schedule prescribed by your doctor.
• Do not stop Clavix-AS suddenly on your own, particularly after a coronary stent or recent cardiovascular event.
• Do not take additional Aspirin, Clopidogrel or other antiplatelet medicines unless your doctor specifically advises them.
• Inform your doctor and dentist that you are taking Clavix-AS before any surgery or dental procedure.
• If you miss a dose, follow your doctor’s or pharmacist’s instructions rather than taking extra medicine.

How It Works

Clavix-AS reduces platelet aggregation through two complementary mechanisms. Clopidogrel is converted in the body to an active metabolite that irreversibly blocks the P2Y12 receptor on platelets, reducing their activation and ability to aggregate. Aspirin irreversibly inhibits platelet COX-1, lowering thromboxane A2 production, another signal that promotes platelet activation. By interfering with these separate pathways, the combination reduces the likelihood of platelet-rich arterial clots developing.

Side Effects

• Easy bruising.
• Nosebleeds.
• Bleeding from the gums.
• Indigestion.
• Stomach discomfort.
• Abdominal pain.
• Diarrhoea.
• Nausea.
• Headache.
• Prolonged or unusual bleeding.
• Skin rash may occur in some patients.

Contact your doctor if side effects persist or if bleeding is unusual or difficult to control.

Precautions & Warnings

• Clavix-AS can cause serious and potentially life-threatening bleeding because it contains two antiplatelet medicines. Seek immediate medical attention for uncontrolled bleeding, vomiting blood, black or bloody stools, blood in the urine, coughing up blood, sudden severe headache or other signs of major bleeding.
• Do not stop Clopidogrel and Aspirin without medical advice, especially after coronary stent placement, because premature interruption can increase the risk of clot formation and serious cardiovascular events.
• Tell your doctor if you have an active stomach ulcer, previous gastrointestinal bleeding, a bleeding disorder, very low platelet counts or another condition that increases bleeding risk.
• Inform your doctor about kidney or liver disease before starting treatment.
• NSAID painkillers and other medicines that affect clotting can increase bleeding risk. Do not add them without medical advice.
• Some medicines can interfere with Clopidogrel activation or increase its antiplatelet effect. Tell your doctor about all prescription medicines, over-the-counter products and supplements you take.
• Inform your doctor before surgery, endoscopy or dental procedures because the medicine may affect procedural bleeding management.
• Avoid unnecessary use of additional Aspirin-containing products unless specifically prescribed.
• Tell your doctor if you develop unexplained bruising, prolonged bleeding or frequent nosebleeds.
• Consult your doctor before using Clavix-AS during pregnancy or breastfeeding.
• Seek urgent medical attention after a significant injury, particularly a head injury, while taking this medicine.
• Do not change the prescribed duration of dual antiplatelet treatment on your own.

Storage Instructions

• Store below 25°C.
• Keep the tablets in their original blister until use.
• Protect from moisture, excessive heat and direct sunlight.
• Keep the medicine in its original packaging.
• Keep out of reach and sight of children.
• Do not use the tablets after the expiry date printed on the package.

FAQs

Q: What is Clavix-AS 75 Tablet used for?
A: Clavix-AS 75 is prescribed for selected cardiovascular conditions where both Aspirin and Clopidogrel are required to reduce arterial clot formation, including certain acute coronary syndromes and situations following coronary intervention.

Q: What does Clavix-AS 75 contain?
A: Each tablet contains Clopidogrel 75 mg and Aspirin 75 mg.

Q: Is Clavix-AS 75 a prescription medicine?
A: Yes. Clavix-AS 75 is a prescription antiplatelet medicine and should be used under medical supervision.

Q: Why are Aspirin and Clopidogrel given together?
A: They reduce platelet activation through different pathways. Using both can provide stronger antiplatelet protection when dual therapy is indicated by a doctor.

Q: Can Clavix-AS 75 cause bleeding?
A: Yes. Increased bleeding is the main important safety concern. Unusual, prolonged or heavy bleeding should be reported promptly.

Q: Who manufactures Clavix-AS 75 Tablet?
A: Clavix-AS 75 Tablet is marketed by Intas Pharmaceuticals Ltd. The commonly listed presentation contains 15 tablets.