Nexpro RD 20 Capsule

Description

Product Description

Nexpro RD 20 Capsule SR is a combination medicine designed for patients who require both acid suppression and improved movement of the upper digestive tract. Each capsule contains Esomeprazole 20 mg and Domperidone 30 mg in a sustained-release formulation. Torrent Pharmaceuticals Ltd. markets this product, which is commonly available in a 10-capsule strip.

Esomeprazole is a proton pump inhibitor that reduces the amount of acid produced by the stomach. Domperidone works mainly on the upper digestive tract, helping stomach contents move forward more normally. Together, these actions can help manage reflux-related symptoms and certain forms of functional digestive discomfort when the combination is considered appropriate by a doctor.

Uses

• Treatment of gastroesophageal reflux disease (GERD) or acid reflux.
• Relief of heartburn associated with excessive stomach acid.
• Management of acid-related upper digestive discomfort.
• May be prescribed for functional dyspepsia in selected patients.
• Helps relieve symptoms that occur when delayed gastric emptying contributes to reflux or indigestion.

Key Benefits

• Combines a proton pump inhibitor with a prokinetic medicine.
• Esomeprazole reduces gastric acid production.
• Domperidone supports movement of food through the upper digestive tract.
• Can address both acid-related symptoms and selected motility-related digestive complaints.
• Sustained-release capsule formulation designed for prescribed treatment.

How to Use

• Take Nexpro RD 20 exactly as prescribed by your doctor.
• Swallow the capsule whole with water.
• Do not crush, chew or open the capsule unless specifically instructed by your doctor or pharmacist.
• It is generally taken on an empty stomach, according to the prescribing instructions for your condition.
• Follow the prescribed duration even if symptoms improve sooner.
• Do not increase, decrease or repeat the dose without medical advice.
• Tell your doctor about all other medicines you take before starting treatment.

How It Works

Nexpro RD 20 works through two complementary mechanisms. Esomeprazole blocks the gastric proton pump responsible for the final stage of acid secretion, thereby lowering stomach-acid production. Domperidone acts mainly as a prokinetic, increasing coordinated movement in the upper gastrointestinal tract and helping gastric contents move onward more efficiently. Reducing acid exposure while supporting gastrointestinal movement can lessen reflux and related digestive symptoms in appropriately selected patients.

Side Effects

• Diarrhoea.
• Abdominal pain or discomfort.
• Flatulence.
• Dry mouth.
• Headache.
• Nausea.
• Dizziness.
• Drowsiness may occur in some people.
• Constipation.
• Changes in bowel habits.

Contact your doctor if side effects persist, become severe or interfere with normal activities.

Precautions & Warnings

• Domperidone can increase the risk of serious heart-rhythm problems, including QT prolongation and potentially life-threatening ventricular arrhythmias. The risk is higher with certain heart conditions, electrolyte abnormalities, and medicines that prolong the QT interval or strongly inhibit CYP3A4. Seek urgent medical attention for fainting, severe dizziness, rapid or irregular heartbeat or unexplained chest symptoms.
• Tell your doctor if you have a history of abnormal heart rhythm, significant heart disease, slow heartbeat or electrolyte disturbances.
• Inform your doctor if you have moderate or severe liver disease because dose selection and continued use may require special consideration.
• Tell your doctor about antibiotics, antifungals, antidepressants, heart medicines and other prescription or non-prescription products you take, particularly medicines that can affect heart rhythm.
• Long-term Esomeprazole treatment may affect magnesium and vitamin B12 levels in some patients and may require monitoring when clinically appropriate.
• Inform your doctor if you have osteoporosis, a history of fractures or other conditions requiring prolonged acid-suppression therapy.
• Tell your doctor if you have unexplained weight loss, difficulty swallowing, persistent vomiting, gastrointestinal bleeding or recurrent severe abdominal pain.
• Consult your doctor before using Nexpro RD during pregnancy or breastfeeding.
• Do not continue self-treatment for persistent acidity without determining the underlying cause.
• Seek medical advice if symptoms do not improve or repeatedly return despite treatment.

Storage Instructions

• Store below 25°C.
• Protect the capsules from moisture and direct light.
• Keep them in the original blister until use.
• Keep the medicine away from excessive heat.
• Store out of reach and sight of children.
• Do not use capsules after the expiry date printed on the package.

FAQs

Q: What is Nexpro RD 20 Capsule used for?
A: Nexpro RD 20 is used mainly for gastroesophageal reflux disease and related acid-reflux symptoms. It may also be prescribed for selected cases of functional dyspepsia.

Q: What does Nexpro RD 20 contain?
A: Each sustained-release capsule contains Esomeprazole 20 mg and Domperidone 30 mg.

Q: Is Nexpro RD 20 a prescription medicine?
A: Yes. Nexpro RD 40 is a prescription medicine and should be used under medical supervision.

Q: Why is Nexpro RD usually taken on an empty stomach?
A: Esomeprazole is commonly taken before food, and your doctor may recommend this timing to obtain the intended acid-suppressing effect. Follow the specific instructions given for your treatment.

Q: Can Nexpro RD 20 affect the heart?
A: Yes. Domperidone can rarely cause serious heart-rhythm disturbances, particularly in people with certain cardiac conditions or when combined with interacting medicines. Medical advice is important before using it.

Q: Who manufactures Nexpro RD 20 Capsule SR?
A: Nexpro RD 40 is marketed by Torrent Pharmaceuticals Ltd.